SARS-CoV-2 (COVID-19) S1 Antibody [5D9]
| Code | Size | Price |
|---|
| PSI-93-311-0.1mg | 0.1mg | £886.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Antibody Isotype: Human IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 5D9
Regulatory Status: RUO
Target Species: Virus
Application: Enzyme-Linked Immunosorbent Assay (ELISA)
Shipping:
blue ice or RT
Storage:
24 months from manufacturing at <-20 ˚C; 1 month, 2 to 8 ˚C under sterile conditions.
Documents
Further Information
Additional Names:
SARS-CoV-2 (COVID-19) Spike S1 Antibody: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein
Application Note:
Immunoreactivity: 80?120 % compared to the reference sample in an ELISA test.
Background:
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Buffer:
PBS, pH 7.4
Concentration:
2.0 mg/ml (+/- 10 %)
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
full length recombinant S Protein
NCBI Gene ID #:
43740568
NCBI Official Name:
surface glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Protein Accession #:
QHD43416
Protein GI Number:
1791269090
Purification:
?95 %
Research Area:
Infectious Disease,COVID-19
SPECIFICITY:
Antibody recognizes 2019-nCoV S1 Protein/ 2019-nCoV S-RBD Protein.
Swissprot #:
QHD43416
User NOte:
Optimal dilutions for each application to be determined by the researcher.