Thymidine Kinase Antibody [3B3.E11]
| Code | Size | Price |
|---|
| PSI-47-130-200ug | 200ug | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 3B3.E11
Regulatory Status: RUO
Target Species: Human
Shipping:
blue ice or RT
Storage:
This antibody is stable for at least one (1) year at -20˚C. Avoid multiple freeze- thaw cycles.
Documents
Further Information
Additional Names:
DNA ligase 1, DNA ligase I,
Background:
Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. High levels of these enzymes are present in proliferating cells, and low levels are found in resting cells, due to multiple regulatory mechanisms that ensure exclusive expression of these enzymes in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.
Buffer:
PBS
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
5?-His-tagged recombinant human thymidine kinase.
NCBI Gene ID #:
3978
NCBI Official Name:
ligase I, DNA, ATP-dependent
NCBI Official Symbol:
LIG1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P18858
Protein GI Number:
118773
Research Area:
Cancer
Swissprot #:
P18858
User NOte:
Optimal dilutions for each application to be determined by the researcher.