Thymidylate Synthase Antibody [2D8.D11]
| Code | Size | Price |
|---|
| PSI-47-129-200ug | 200ug | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 2D8.D11
Regulatory Status: RUO
Target Species: Human
Shipping:
blue ice or RT
Storage:
This antibody is stable for at least one (1) year at -20˚C. Avoid multiple freeze- thaw cycles.
Documents
Further Information
Additional Names:
RAD51A, RECA, DNA repair protein RAD51 homolog 1, RAD51 homolog A, HsRAD51, BRCC5, MRMV2, HRAD51, HsRad51, HsT16930
Background:
Thymidylate synthase (TS) is anintracellular enzyme critical for de novosynthesis of DNA. In cancer,expression of TS is often elevated and becomes further elevated as a result of treatment with the most commonly used chemotherapeutic, 5-fluorouracil (5-FU). Resistance or lack of response to 5-FU is attributed to the elevation of TS activity. Overexpression of TS has been demonstrated in many types of tumors including breast, colon, gastric and melanoma and is usually predictive of shortened survival time.
Buffer:
PBS
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Recombinant human thymidylate synthase produced in E. coli.
NCBI Gene ID #:
5888
NCBI Official Name:
RAD51 recombinase
NCBI Official Symbol:
RAD51
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_001157741.1
Protein GI Number:
256017143
Research Area:
Cancer
Swissprot #:
Q06609
User NOte:
Optimal dilutions for each application to be determined by the researcher.