Rosuvastatin . calcium salt
| Code | Size | Price |
|---|
| PSI-10-041-250mg | 250mg | £409.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
blue ice
Storage:
Short Term Storage: +4C. Long Term Storage: -20C. Handling Advice: Keep cool and dry. Use/Stability: Stable for at least 2 years after receipt when stored at -20C.
Documents
Further Information
Additional Names:
Crestor
Background:
Rosuvastatin is a potent competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme in the cholesterol biosynthetic pathway and the target of the statin class of cholesterol-lowering drugs. Rosuvastatin is antilipemic and is used to reduce plasma cholesterol levels and prevent cardiovascular disease. Formulations containing rosuvastatin reduce low-density lipoprotein (LDL) and C-reactive protein and increase high-density lipoprotein (HDL) in humans. Shown to have anti-inflammatory, antioxidant, antithrombotic and insulin sensitizing properties. Identified as a potential inhibitor of SARS-CoV-2, responsible for COVID-19.
CAS:
147098-20-2
Formula:
C22H27FN3O6S . 1/2Ca
Identity:
Determined by 1H-NMR.
InChi Key:
VGAZDTHGPVFCCO-YFRSHGDPSA-K
Physical State:
Lyophilized
Predicted Molecular Weight:
480.6 . 20.0
Purity:
greater than or equal to 98% (HPLC)
Rtecs:
MJ9675070
Smiles:
CN(S(C)(=O)=O)C1=NC(C2=CC=C(F)C=C2)=C(/C=C/[C@H](C[C@@H](O)CC([O-])=O)O)C(C(C)C)=N1.[Ca+2]
Solubility:
Soluble in DMSO or ethanol. Insoluble in water.
Soluble In Dmf, Ethanol, Dmso Or Aqueous Solvents (Pbs).:
Soluble in DMSO or ethanol. Insoluble in water.