Natalizumab (ITGA4/CD49d) Antibody, Monoclonal

ProSci
Product Code: PSI-10-090
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-10-090-0.1mg0.1mg£657.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: IgG4-kappa
Antibody Clonality: Recombinant Antibody
Regulatory Status: RUO
Shipping:
blue ice
Storage:
Store at -80˚C

Images

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SDS-PAGE Image

SDS-PAGE Image

Further Information

Additional Names:
AN 100226,BG00002, ITGA4/CD49d, ITGA4/CD49d
Background:
Natalizumab is a recombinant, humanized monoclonal antibody,binds to ?4?1-integrin?and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1).Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.
Buffer:
PBS buffer pH7.5
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Humanized / ITGA4/CD49d [Homo sapiens]
NCBI Organism:
homo sapiens
Purification:
>95%
Research Area:
Drug Analogues
Source:
CHO cells
Swissprot #:
P13612
User NOte:
Optimal dilutions for each application to be determined by the researcher.