SARS-CoV-2 (COVID-19) S Protein RBD-SD1 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-736-0.05mg | 0.05mg | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
blue ice or RT
Storage:
Reconstituted protein solution should be store below -20˚C.
Documents
Further Information
Additional Names:
2019-nCov RBD Protein; 2019-nCoV Spike RBD Protein
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
Buffer:
Supplied as a 0.2 uM filtered solution of PBS,PH7.4.
Fusion Tag:
C-6His tag
NCBI Gene ID #:
43740568
NCBI Official Name:
Surface glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Predicted Molecular Weight:
31.4kDa, 35-43kDa
Protein Accession #:
QHD43416.1
Purity:
Greater than 95% as determined by reducing SDS-PAGE/SEC-HPLC.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Mammalian Cells
Swissprot #:
QHD43416.1