SARS-CoV-2 (COVID-19) Envelope Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-730-0.1mg | 0.1mg | £469.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: E.coli
Regulatory Status: RUO
Shipping:
blue ice or RT
Storage:
Reconstituted protein solution should be store below -20˚C.
Documents
Further Information
Additional Names:
2019-nCoV E protein; 2019-nCoV sM protein
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Buffer:
Supplied as a 0.2 uM filtered solution of 20mM Tris–HCl, 200mM NaCl, pH 8.0
Fusion Tag:
N-BBP-6His tag
NCBI Gene ID #:
43740570
NCBI Official Name:
Envelope protein
NCBI Official Symbol:
E
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Predicted Molecular Weight:
27.5kDa, 22-25kDa
Protein Accession #:
QHD43418.1
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
QHD43418.1