ACE-2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-92-724-0.05mg | 0.05mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Shipping:
blue ice or RT
Storage:
Store below -20˚C, stable for 6 months after receipt.
Documents
Further Information
Additional Names:
Angiotensin-Converting Enzyme 2; ACE-Related Carboxypeptidase; Angiotensin-Converting Enzyme Homolog; ACEH; Metalloprotease MPROT15; ACE2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate levels. Captopril and lisinopril as the classical ACE inhibitor don??™t inhibit ACE-2 activity. ACE-2 may play an important role in regulating the heart function.
Buffer:
Supplied as a 0.2 um filtered solution of 25mM Tris-HCl, 150mM NaCl, 1mM ZnCl2, pH 7.5.
Fusion Tag:
C-10 His tag
NCBI Gene ID #:
70008
NCBI Official Name:
Angiotensin-converting enzyme 2
NCBI Official Symbol:
Ace2
NCBI Organism:
Mus musculus
Physical State:
Liquid
Predicted Molecular Weight:
84.9KDa
Protein Accession #:
Q8R0I0
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Mammalian Cells
Swissprot #:
Q8R0I0