SARS-CoV-2 (COVID-19) NSP3 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-10-406-0.1mg | 0.1mg | £657.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: E.coli
Regulatory Status: RUO
Shipping:
blue ice or RT
Storage:
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 ˚C for one week. Store at -20 to -80 ˚C for twelve months from the date of receipt.
Documents
Further Information
Additional Names:
nsp3,PL-PRO,Papain-like proteinase,X domain (Macro domain)
Application Note:
Immunogen
Background:
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
Buffer:
Supplied as lyophilized from PBS, pH 7.5. Please reconstitute the protein with ddH2O to the concentration with 1mg/ml.
Fusion Tag:
N-His Tag
Physical State:
Lyophilized
Predicted Molecular Weight:
22.03kDa
Protein Accession #:
QHD43415.1
Purity:
>90% as determined by SDS-PAGE quantitative densitometry by Coomassie Blue Staining.
Recombinant Protein Sequence:
#N/A
Source:
E. coli