anti-Hex1 (Neurospora crassa) mAb (rec.) (SH1237-F8)

Woronin Body Major Protein

1 mg/ml

32160000

liquid

Liquid. In PBS.

After opening, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Please handle under sterile conditions to avoid contamination.

Synthetic biotinylated Hex-1 (Neurospora crassa) peptide.

Recombinant Antibody. Recognizes Hex1 from Neurospora crassa. Applications: ELISA, IGS. Clone: SH1237-F8. Isotype: Human IgG1. Formulation: Liquid. In PBS. Neurospora crassa has been an excellent model organism for eukaryotic genetics and biochemistry and one of the workhorses for fungal cell biology research. The rapid (mm~4 hr/1) filamentous growth habit of N. crassa is the result of a strongly polarized mechanism culminating in the biogenesis of the tubular cell wall. Woronin bodies (WBs)peroxisome-related are membrane-bound organelles of filamentous ascomycetes that mediate hyphal compartmentalization by plugging septal pores upon hyphal damage. Their major component is the peroxisomal protein HEX-1, which has also been implicated in additional cellular processes in fungi.

P87252

This is an antibody developed by antibody phage display technology using a human naive antibody gene library. These libraries consist of scFv (single chain fragment variable) composed of VH (variable domain of the human immunoglobulin heavy chain) and VL (variable domain of the human immunoglobulin light chain) connected by a polypeptide linker. The antibody fragments are displayed on the surface of filamentous bacteriophage (M13). This scFv was selected by affinity selection on antigen in a process termed panning. Multiple rounds of panning are performed to enrich for antigen-specific scFv-phage. Monoclonal antibodies are subsequently identified by screening after each round of selection. The selected monoclonal scFv is cloned into an appropriate vector containing a Fc portion of interest and then produced in mammalian cells to generate an IgG like scFv-Fc fusion protein.

Vial

Neurospora crassa has been an excellent model organism for eukaryotic genetics and biochemistry and one of the workhorses for fungal cell biology research. The rapid (mm~4 hr/1) filamentous growth habit of N. crassa is the result of a strongly polarized mechanism culminating in the biogenesis of the tubular cell wall. Woronin bodies (WBs)peroxisome-related are membrane-bound organelles of filamentous ascomycetes that mediate hyphal compartmentalization by plugging septal pores upon hyphal damage. Their major component is the peroxisomal protein HEX-1, which has also been implicated in additional cellular processes in fungi.

>95% (SDS-PAGE)

Protein A purified from HEK293 cell culture supernatant.

Recognizes Hex1 from Neurospora crassa.

Non-hazardous

Primary Antibodies

12352203

Stable for at least 1 year after receipt when stored at -20°C.Stable for at least 1 week when stored at +4°C.