SARS-CoV-2 Nucleocapsid Antibody, monoclonal

ProSci
Product Code: PSI-11-589
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-11-589-0.1mg0.1mg£765.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Antibody Isotype: Human IgG1/kappa
Antibody Clonality: Monoclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
blue ice or RT
Storage:
For long term storage, the product should be stored at lyophilized state at -20˚C or lower..Please avoid repeated freeze-thaw cycles.This product is stable after storage at:.-20 to -70˚C for 12 months in lyophilized state from date of receipt;.-70˚C for 3 months under sterile conditions after reconstitution.

Images

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Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
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Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 on SDS-PAGE under reducing (R) and non-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.

Further Information

Additional Names:
SARS-CoV-2 Nucleocapsid Protein, SARS-CoV-2 NP, nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2], novel coronavirus N Protein, novel coronavirus Nucleocapsid Protein, 2019-nCoV Nucleoprotein, 2019-nCoV N, 2019nCoV N, 2019-nCoV N Protein, 2019 peak N Protein, 2019-nCoV nucleocapsid protein.
Application Note:
This antibody can be paired with other Anti-SARS-CoV-2 Nucleocapsid antibodies to detect SARS-CoV-2 Nucleocapsid protein in sandwich ELISA or LFA assay.
Background:
Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.
Buffer:
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 . Normally trehalose is added as protectant before lyophilization.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Anti-SARS-CoV-2 Nucleocapsid Antibody, Human IgG1 is isolated from a SARS-CoV-2 infected patient and is recombinantly produced from human 293 cells (HEK293).
NCBI Gene ID #:
1489678
NCBI Official Name:
nucleocapsid phosphoprotein
NCBI Official Symbol:
N
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Lyophilized
Purification:
>95% as determined by SDS-PAGE.
Research Area:
Infectious Disease, COVID-19, Antibody Pairs
SPECIFICITY:
This product can recognize SARS-CoV-2 and SARS-CoV Nucleocapsid protein. No cross-reactivity is detected with nucleocapsid protein of other coronaviruses, including MERS-CoV, HCoV-229E, HCoV-NL63, HCoV-OC43 and HCoV-HKU1.
Swissprot #:
P0DTC9
User NOte:
Optimal dilutions for each application to be determined by the researcher.