SARS-CoV-2 (COVID-19) NSP12 Antibody

ProSci
Product Code: PSI-9267
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-9267-0.02mg0.02mg£150.00
Quantity:
PSI-9267-0.1mg0.1mg£449.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Virus
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
blue ice or RT
Storage:
SARS-CoV-2 (COVID-19) NSP12 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Further Information

Additional Names:
RNA-directed RNA polymerase, Pol, RdRp,?NSP12, Non-structure protein 12
Application Note:
WB: 1-2 μg/mL

Antibody validated: SARS-CoV-2 (COVID-19) NSP12 antibody can detect 2 ng of free peptide at 1 ?g/mL in ELISA. It can detect SARS-CoV-2 NSP12 recombinant protein by ELISA and WB. All other applications and species not yet tested.
Background:
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019?20 coronavirus outbreak (2). The structure of 2019-nCoV consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. NSP12 interacts with nsp7 and nsp8.
Background References:
  • Gorbalenya. bioRxiv: 2020.
  • Hui et al. Int J Infect Dis. 2020;91:264-266.
Buffer:
SARS-CoV-2 (COVID-19) NSP12 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Predicted reactivity based on immunogen sequence: SARS-CoV NSP12 protein: (100%).
Immunogen:
Anti-SARS-CoV-2 (COVID-19) NSP12 antibody (9267) was raised against a peptide corresponding to 16 amino acids near the carboxyl terminus of SARS-CoV-2 (COVID-19) NSP12 protein.

The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) NSP12 protein.
NCBI Gene ID #:
43740578
NCBI Official Name:
ORF1a polyprotein;ORF1ab polyprotein
NCBI Official Symbol:
ORF1ab
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Protein Accession #:
7B3D_A
Protein GI Number:
1951688606
Purification:
SARS-CoV-2 (COVID-19) NSP12 antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease,COVID-19
Swissprot #:
P0DTC1
User NOte:
Optimal dilutions for each application to be determined by the researcher.