SARS-CoV-2 (COVID-19) ORF3b Antibody
Code | Size | Price |
---|
PSI-9277-0.02mg | 0.02mg | £150.00 |
Quantity:
PSI-9277-0.1mg | 0.1mg | £449.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Virus
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
blue ice or RT
Storage:
SARS-CoV-2 (COVID-19) ORF3b antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Further Information
Additional Names:
ORF3b protein, Acessary protein 3b, ns3b, Non-structural protein 3b, ORF3b
Application Note:
WB: 0.1 μg/mL
Antibody validated: SARS-CoV-2 (COVID-19) ORF3b antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 ORF3b recombinant protein by ELISA and WB. All other applications and species not yet tested.
Antibody validated: SARS-CoV-2 (COVID-19) ORF3b antibody can detect 2 ng of free peptide at 1 μg/mL in ELISA. It can detect SARS-CoV-2 ORF3b recombinant protein by ELISA and WB. All other applications and species not yet tested.
Background:
Coronavirus disease 2019 (COVID-19), formerly known as 2019-nCoV acute respiratory disease, is an infectious disease caused by SARS-CoV-2, a virus closely related to the SARS virus (1). The disease is the cause of the 2019?20 coronavirus outbreak (2). SARS-CoV-2 virus proteins include structural proteins, non-structural proteins and accessory factors. The structure of SARS-CoV-2 consists of the following: a spike protein (S), hemagglutinin-esterease dimer (HE), a membrane glycoprotein (M), an envelope protein (E) a nucleoclapid protein (N) and RNA. SARS-CoV-2 non-structural protein is ORF1ab that consists of 16 proteins (nsp1-nsp16), while accessory factors include ORF3a, ORF3b, ORF6, ORF7a, ORF7b, ORF3b, ORF9b, ORF9c and ORF10.
ORF3b may play a role in interferon antiviral system evasion (3).
Background References:
- Gorbalenya. bioRxiv: 2020.
- Hui et al. Int J Infect Dis. 2020;91:264-266.
- Konno et al. Cell Rep. 2020; 32:108185.
Buffer:
SARS-CoV-2 (COVID-19) ORF3b antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Anti-SARS-CoV-2 (COVID-19) ORF3b antibody (9277) was raised against a peptide corresponding to 12 amino acids near carboxyl terminus of SARS-CoV-2 (COVID-19) ORF3b protein.
The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF3b protein.
The immunogen is located within the last 50 amino acids of the SARS-CoV-2 (COVID-19) ORF3b protein.
NCBI Gene ID #:
43740569
NCBI Official Name:
ORF3a protein
NCBI Official Symbol:
ORF3a
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
17kD
Protein Accession #:
P0DTC3
Protein GI Number:
1835921851
Purification:
SARS-CoV-2 (COVID-19) ORF3b Antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease,COVID-19
SPECIFICITY:
ORF3b Antibody is predicted to not cross-react with other coronavirus family members.
Swissprot #:
P0DTC4
User NOte:
Optimal dilutions for each application to be determined by the researcher.