SARS-CoV-2 (COVID-19) NSP16 Antibody
| Code | Size | Price |
|---|
| PSI-20-276-0.1mg | 0.1mg | £758.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Sheep
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Virus
Application: Western Blot (WB)
Shipping:
dry ice
Storage:
Aliquot and store at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Documents
Further Information
Additional Names:
SARS-CoV-2-NSP16
Application Note:
Detection Antibodies: 1 μg/ml Ab, 5% BSA in TBS-T, 4˚C overnight
Blocking: 5% milk in TBS-T, 1h room temp
Secondary Antibodies: 1:15,000 donkey anti-sheep, 1:15,000 donkey anti-rabbot, in TBS-T, 1h room temp
Wash: TBS-T, 4x 10 min
Blocking: 5% milk in TBS-T, 1h room temp
Secondary Antibodies: 1:15,000 donkey anti-sheep, 1:15,000 donkey anti-rabbot, in TBS-T, 1h room temp
Wash: TBS-T, 4x 10 min
Background:
The coronaviral proteases, papain-like protease (PLpro) and 3C-like protease (3CLpro), are attractive antiviral drug targets because they are essential for coronaviral replication. PLpro has the additional function of stripping ubiquitin and ISG15 from host-cell proteins to aid coronaviruses in their evasion of the host innate immune responses. Targeting PLpro with antiviral drugs may have an advantage in not only inhibiting viral replication but also inhibiting the dysregulation of signaling cascades in infected cells that may lead to cell death in surrounding, uninfected cells.
Buffer:
Antibody supplied in PBS.
Concentration:
batch dependent
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
GST-SARS-CoV2 NSP16
Molecular Weight:
60 kDa
NCBI Gene ID #:
43740578
NCBI Official Name:
ORF1a polyprotein;ORF1ab polyprotein
NCBI Official Symbol:
ORF1ab
NCBI Organism:
Severe acute respiratory syndrome coronavirus 2
Physical State:
Liquid
Purification:
Antibodies are affinity purified against the antigen and eluted with low pH.
Research Area:
Infectious Disease,COVID-19
Swissprot #:
P0DTC1
User NOte:
Optimal dilutions for each application to be determined by the researcher.