IL-24 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-600-0.005mg | 0.005mg | £300.00 |
Quantity:
| PSI-40-600-0.02mg | 0.02mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Hamster
Regulatory Status: RUO
Target Species: Human
Shipping:
blue ice or RT
Storage:
The lyophilized IL-24 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-24 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-24 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Documents
Further Information
Additional Names:
C49A, FISP, MDA7, MOB5, ST16, IL10B, Interleukin-24, Melanoma differentiation-associated gene 7 protein, IL-24
Background:
IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.
NCBI Gene ID #:
11009
NCBI Official Name:
interleukin 24
NCBI Official Symbol:
IL24
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001172085.1
Protein GI Number:
297632401
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
Q13007