NKp46 / NCR1 / CD335 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-293-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
NCR1,LY94,CD335,NK-p46,hNKp46
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 28.3 kDa. The protein migrates as 36-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Natural cytotoxicity triggering receptor 1 (NCR1) is also known as Natural killer cell p46-related protein (NK-p46), Lymphocyte antigen 94 homolog (LY94), CD antigen CD335, which belongs to the natural cytotoxicity receptor (NCR) family. NCR1 contains two Ig-like (immunoglobulin-like) domains. NCR1 interacts with CD247 and FCER1G. NCR1 / CD335 may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
Background References:
- Pessino A., et al., 1998, J. Exp. Med. 188:953-960.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
9437
NCBI Official Name:
naturalcytotoxicitytriggeringreceptor1
NCBI Official Symbol:
NCR1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
28.3 kDa
Protein Accession #:
AAH64806.1
Purity:
>90% as determined by reduced SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
O76036