Netrin receptor DCC / DCC Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-111-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
Netrin receptor DCC,DCC,IGDCC1,netrin receptor DCC
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 144.1 kDa. The protein migrates as 140-160 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.
Buffer:
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
1630
NCBI Official Name:
DCCnetrin1receptor
NCBI Official Symbol:
DCC
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
144.1 kDa
Protein Accession #:
NP_005206.2
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P43146