CD24 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-274-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CD24,CD24A
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 5.0 kDa. The protein migrates as 19-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Background References:
- Suzuki T1, et al. 2001. J Immunol. 166(9):5567-77.
- Chen Z, et al. 2017. Biomed Pharmacother. 90:427-436.
- Eyvazi S, et al. 2018. Curr Cancer Drug Targets. 18(4):328-336.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
100133941
NCBI Official Name:
CD24molecule
NCBI Official Symbol:
CD24
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
5.0 kDa
Protein Accession #:
NP_001278666.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P25063