CD3 epsilon&CD3 gamma Heterodimer Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-551-0.05mg | 0.05mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CD3 epsilon & CD3 gamma,CD3E & CD3G
Application Note:
Human CD3E&CD3G Heterodimer Protein, Fc,His Tag&Fc,Flag Tag is produced by co-expression of CD3E and CD3G, has a calculated MW of 39.2 kDa (CD3E) and 38.6 kDa (CD3G). Subunit CD3E is fused with a human IgG1 Fc tag at the C-terminus, followed by a polyhist
Background:
T-cell surface glycoprotein CD3 delta & CD3 gamma chain, also known as CD3D & CD3G or CD3D&CD3G respectively, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Background References:
- Gold DP, et al., 1986, Nature 321 (6068): 431?4.
- Clevers HC, et al., 1988, Proc. Natl. Acad. Sci. U.S.A. 85 (21): 8156?60.
- Gil J, et al., 2011, J Clin Invest, 121(10):3872-6.
- Lu X, et al.,2011, Hematology, 16(3):185-9.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag & Fc Tag & Flag Tag
NCBI Gene ID #:
916
NCBI Official Name:
CD3e molecule
NCBI Official Symbol:
CD3E
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
39.2 kDa (CD3E) & 38.6 kDa (CD3G)
Protein Accession #:
NP_000724.1 (CD3E) & AAI13831.1 (CD3G)
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P07766