CD52 Recombinant Protein

ProSci
Product Code: PSI-11-502
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-11-502-0.1mg0.1mg£657.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

Documents

Further Information

Additional Names:
CDW52,HE5,CD52,CAMPATH-1 antigen
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 27.9 kDa. The protein migrates as 38-43 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
CAMPATH-1 antigen, also known as cluster of differentiation 52 (CD52), is a glycoprotein that in humans is encoded by the CD52 gene.It is widely expressed on the cell surface of immune cells, such as mature lymphocytes, natural killer cells (NK), eosinophils, neutrophils, monocytes/macrophages, and dendritic cells (DCs).ligation of cell surface CD52 molecules may offer costimulatory signals for T-cell activation and proliferation.
Background References:
  • Zhao Y., et al., 2017 ,Immunogenetics.
  • Hersh C., et al., 2014, Immunotherapy. 6(3):249-59.
  • Zinzani PL., et al., 2012, Leuk Lymphoma. 53(5):789-9
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
1043
NCBI Official Name:
CD52 molecule
NCBI Official Symbol:
CD52
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
27.9 kDa
Protein Accession #:
NP_001794.2
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
P31358