IL-17 RE (155-454) Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-285-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
IL-17 RE,IL17RE,IL-17RE,IL-17 receptor E
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 60.5 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Interleukin-17 receptor E (IL-17 RE) is an orphan receptor of the IL-17 receptor family, also known as UNQ3056, PRO9877, IL-17 Receptor E. IL-17RE is known to be expressed in the pancreas, brain, and prostate. IL-17RE is a receptor specific to IL-17C and has an essential role in host mucosal defense against infection. IL-17C functioned in a unique autocrine manner, binding to a receptor complex consisting of the receptors IL-17RA and IL-17RE, which was preferentially expressed on tissue epithelial cells. Some data identify IL-17RE as a receptor of IL-17C that regulates early innate immunity to intestinal pathogens.
Background References:
- Song X. Nat Immunol. 2011. 12(12):1151-8.
- Ramirez-Carrozzi V. Nat Immunol. 2011. 12(12):1159-66.
- Pfeifer P. Am J Respir Cell Mol Biol. 2013. 48(4):415-21.
Buffer:
Tris?with?Glycine,?Arginine?and?NaCl,?pH7.5
Fusion Tag:
Fc Tag
NCBI Gene ID #:
132014
NCBI Official Name:
interleukin17receptorE
NCBI Official Symbol:
IL17RE
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
60.5 kDa
Protein Accession #:
NP_705613.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q8NFR9