Siglec-9 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-298-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Human
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
Siglec-9,SIGLEC9,CDw329,CD329
Application Note:
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 62.5 kDa. The protein migrates as 80-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
siglec-9 (HGMW-approved symbol SIGLEC9) a member of the sialic acid-binding Ig-like lectin (Siglec) family, which belongs to the immunoglobulin superfamily (IgSF). SIGLEC9 shows a high degree of homology to many members of the siglec family, including siglec-7 (80%), siglec-8 (72%), siglec-5 (65%), and CD33 (64%). This high degree of homology is also conserved in the extracellular Ig-like domains. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains Siglec-9 with a hydrophobic signal peptide, an N-terminal Ig-likeV-type domain, two Ig-like C2-type domains, a transmembrane region and a cytoplasmic tail.
Background References:
- Foussias G, et al. Genomics. 2000. 67(2):171-8.
- Liu YC, et al. Front Immunol. 2017. 8:1601.
- Angata T, et al. J Biol Chem. 2000. 275(29):22127-35.
Buffer:
PBS, pH7.4
Fusion Tag:
Fc Tag
NCBI Gene ID #:
27180
NCBI Official Name:
sialicacidbindingIglikelectin9
NCBI Official Symbol:
SIGLEC9
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
62.5 kDa
Protein Accession #:
NP_055256.1
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q9Y336