TROP-2 / TACSTD2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-191-0.2mg | 0.2mg | £597.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Mouse
Application: Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
TACSTD2,GA733-1,M1S1,TROP2
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 29.9 kDa. The protein migrates as 38-48 kDa under reducing (R) condition (SDS-PAGE) due to Glycosylation.
Background:
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
Background References:
- Simms A., et al., 2016, Diagn. Cytopathol. 44:26-31.
- Fornaro M., et al., 1995, Int. J. Cancer. 62(5):610-618.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
56753
NCBI Official Name:
tumor-associatedcalciumsignaltransducer2
NCBI Official Symbol:
Tacstd2
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
29.9 kDa
Protein Accession #:
NP_064431.2
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells
Swissprot #:
Q8BGV3