Rhesus macaque SLAMF7 / CRACC / CD319 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-463-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Rhesus Macaque
Application: Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
SLAMF7,CD319,CS1,CRACC,19A,FOAP-12
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 24.4 kDa. The protein migrates as 35-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
Background References:
- Bouchon A., et al., 2001, J. Immunol. 167:5517-5521.
- Murphy J.J., et al., 2002, Biochem. J. 361:431-436.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
Physical State:
Lyophilized
Predicted Molecular Weight:
24.4 kDa
Protein Accession #:
XP_001117618.1
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells