Rhesus macaque CTGF / CCN2 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-11-218-0.1mg | 0.1mg | £729.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Human
Regulatory Status: RUO
Target Species: Rhesus Macaque
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Shipping:
blue ice or RT
Storage:
Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Additional Names:
CCN2,NOV2,HCS24,IGFBP8,IBP-8,IGFBP-8,IGF-binding protein 8
Application Note:
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 37.3 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Background:
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
Background References:
- Faith Hall-Glenn., et?al. 2011, Cell Mol Life Sci., 68(19), 3209?3217.
- Nakanishi T., et?al. 2000, Endocrinology., 141(1), 264-73.
- Ball DK., et?al. 2000, J Endocrinol., 176(2), R1-7.
Buffer:
5 mM HAC,100 mM NaCl, pH 5.5
Fusion Tag:
His Tag
Physical State:
Lyophilized
Predicted Molecular Weight:
37.3 kDa
Purity:
>90% as determined by SDS-PAGE.
Recombinant Protein Sequence:
#N/A
Source:
HEK293 cells