SARS CoV-2 full length spike protein in LMNG detergent

SARS-CoV-2 (COVID-19) Spike Recombinant Protein: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Surface Glycoprotein, Spike protein

This recombinant protein can be used for ELISA assays, Ligand binding assays (e.g. SPR), Biochemical and biophysical analyses. For research use only.

The coronavirus, also known as SARS-CoV-2, enters the cell by using its surface SPIKE. SPIKE is processed on the cell's surface by TMPRSS2, a serine protease. It then subsequently binds to ACE2 a cell surface receptor. The Native SPIKE protein is a trimer that is located in the coronavirus membrane. Therefore to get pure & native SPIKE the trimer needs to be kept intact. Our lab staff achieved this in three different ways: MSP nanodiscs, based on MSP proteins Detergent Mycelles, as you can see here Synthetic nanodiscs

not determined

20 mM Hepes pH 7.5; 150 mM NaCl, 0.01 % LMNG

batch dependent

C-terminal Rho1D4

43740568

surface glycoprotein

S

Severe acute respiratory syndrome coronavirus 2

Liquid

1286 amino acids (including Rho1D4 tag and linker); 142114 Da

>98% as determined by SDS-PAGE, see Fig. 1 A and B. PureCube Rho1D4 Agarose.

#N/A

HEK293 cells

P0DTC2