IL-36gamma Recombinant Protein

ProSci
Product Code: PSI-40-603
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-40-603-0.002mg0.002mg£300.00
Quantity:
PSI-40-603-0.01mg0.01mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: E.coli
Regulatory Status: RUO
Target Species: Human
Shipping:
blue ice or RT
Storage:
The lyophilized IL-36gama recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted IL-36gama is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing IL-36gama recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Documents

Further Information

Additional Names:
IL1E, IL1F9, IL1H1, IL-1F9, IL-1H1, IL1RP2, IL-1RP2, IL1E, UNQ2456/PRO5737, Interleukin-36 gamma, IL-1-related protein 2
Background:
The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36α (IL-1F6), β (IL-1F8) and γ (IL-1F9). IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-kappaB, and can stimulate the inflammatory response in bronchial epithelial cells. Recombinant human IL-36γ is a 17.0 kDa protein containing 152 amino acid residues.
NCBI Gene ID #:
56300
NCBI Official Name:
interleukin 36, gamma
NCBI Official Symbol:
IL36G
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001265497.1
Protein GI Number:
514388113
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q9NZH8