TPO Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-585-0.002mg | 0.002mg | £300.00 |
Quantity:
| PSI-40-585-0.01mg | 0.01mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: E.coli
Regulatory Status: RUO
Target Species: Rat
Shipping:
blue ice or RT
Storage:
The lyophilized TPO recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted TPO stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing TPO recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Documents
Further Information
Additional Names:
Thrombopoietin
Background:
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes, and promotes increased circulating levels of platelets in vivo. TPO signals through the c-mpl receptor and acts as an important regulator of circulating platelets. Human and murine TPO exhibits cross-species reactivity. Recombinant rat TPO is a fully biologically active 174 amino acid polypeptide (18.7 kDa), which contains the erythropoietin-like domain of the full length TPO protein.
Biological Activity:
Biological activity was determined by its ability to stimulate the proliferation of human MO7e cells. The expected B>ED50 is ≤ 0.2 ng/mL, corresponding to a specific activity of ≥ 5 x 106 units/mg. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
81811
NCBI Official Name:
thrombopoietin
NCBI Official Symbol:
Thpo
NCBI Organism:
Rattus norvegicus
Physical State:
Lyophilized
Protein Accession #:
NP_112395.1
Protein GI Number:
13592113
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P49745