Betacellulin Recombinant Protein

ProSci
Product Code: PSI-40-578
Product Group: Recombinant Proteins
Supplier: ProSci
CodeSizePrice
PSI-40-578-0.005mg0.005mg£300.00
Quantity:
PSI-40-578-0.02mg0.02mg£428.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: E.coli
Regulatory Status: RUO
Target Species: Mouse
Shipping:
blue ice or RT
Storage:
The lyophilized Betacellulin recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted Betacellulin stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing Betacellulin recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Documents

Further Information

Additional Names:
Bcn, Bcn, Probetacellulin, BTC
Background:
Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. Betacellulin is initially synthesized as a glycosylated 32.0 kDa transmembrane precursor protein, which is processed by proteolytic cleavage to produce the mature sequence. Recombinant murine Betacellulin is a 9.0 kDa monomeric protein, containing 80 amino residues, which comprises the mature EGF homologous portion of the Betacellulin protein.
Biological Activity:
Biological activity was determined by its ability to stimulate the proliferation of mouse Balb/3T3 cells. The expected ED50 is ≤ 0.01 ng/mL, corresponding to a specific activity of ≥ 1 x 108 units/mg. Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
12223
NCBI Official Name:
betacellulin, epidermal growth factor family member
NCBI Official Symbol:
Btc
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
NP_031594.1
Protein GI Number:
6680812
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
Q05928