GDF-5 Recombinant Protein
| Code | Size | Price |
|---|
| PSI-40-579-0.01mg | 0.01mg | £300.00 |
Quantity:
| PSI-40-579-0.05mg | 0.05mg | £428.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: E.coli
Regulatory Status: RUO
Target Species: Mouse
Shipping:
blue ice or RT
Storage:
The lyophilized GDF-5 recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted GDF-5 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing GDF-5 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Documents
Further Information
Additional Names:
OS5, LAP4, BDA1C, BMP14, CDMP1, SYM1B, SYNS2, Cartilage-derived morphogenetic protein 1, GDF-5
Background:
GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Grebe Syndrome, which is characterized by short stature, extra digits, short and deformed extremities, and in Hunter-Thompson type dwarfism. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino-acid signal peptide and a 348 amino-acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant murine GDF-5 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acids.
Biological Activity:
Endotoxin level is less than 0.1 ng per μg (1EU/μg).
NCBI Gene ID #:
8200
NCBI Official Name:
growth differentiation factor 5
NCBI Official Symbol:
GDF5
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000548.1
Protein GI Number:
4503969
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P43026