Daidzin
| Code | Size | Price |
|---|
| CDX-D0926-M005 | 5 mg | £41.00 |
Quantity:
| CDX-D0926-M025 | 25 mg | £132.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +20°C, Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
Daidzein-7-O-beta-D-glucopyranoside; Daidzoside; NPI 031D; BRN 0059741
Appearance:
White powder.
CAS:
552-66-9
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C21H20O9/c22-8-16-18(25)19(26)20(27)21(30-16)29-12-5-6-13-15(7-12)28-9-14(17(13)24)10-1-3-11(23)4-2-10/h1-7,9,16,18-23,25-27H,8H2/t16-,18-,19+,20-,21-/m1/s1
InChiKey:
KYQZWONCHDNPDP-QNDFHXLGSA-N
Long Description:
Chemical. CAS: 552-66-9. Formula: C21H20O9. MW: 416.38. Daidzin is a naturally occuring isoflavone. It is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (ALDH-2) (IC50=80nM) and is an effective anti-dipsotropic isoflavone.
MDL:
MFCD00017466
Molecular Formula:
C21H20O9
Molecular Weight:
416.38
Package Type:
Vial
Product Description:
Daidzin is a naturally occuring isoflavone. It is the major active component of the traditional Chinese medicine (TCM) derived from radix puerariae (Kudzu) that is commonly used to treat alcohol abuse. Like other isoflavones, daidzin has anti-oxidant, anti-carcinogenic and anti-atherosclerotic activities. Daidzin directly inhibits mitochondrial aldehyde dehydrogenase 2 (ALDH-2) (IC50=80nM) and is an effective anti-dipsotropic isoflavone.
Purity:
>98% (HPLC)
SMILES:
O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O)=CC=C31
Solubility Chemicals:
Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (2mg/ml).
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) W.M. Keung & B.L. Vallee; PNAS 90, 1247 (1993) | (2) C.I. Xie, et al.; Alcohol Clin. Exp. Res. 18, 1443 (1994) | (3) W.M. Keung & B.L. Vallee; PNAS 95, 2198 (1998) | (4) K. Kato, et al.; Jpn. J. Cancer Res. 91, 786 (2000) | (5) X.H. Li, et al.; Acta Pharmacol. Sin. 26, 1081 (2005) | (6) E.D. Lowe, et al.; J. Med. Chem. 51, 4482 (2008) | (7) Y. Zang, et al.; Biosci. Biotechnol. Biochem. 79, 117 (2015) | (8) G. Wei, et al.; J. Cell Biochem. 120, 5304 (2019)