Protodioscin
| Code | Size | Price |
|---|
| CDX-P0451-M010 | 10 mg | £102.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +20°C Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
NSC 698796
Appearance:
White to off-white powder.
CAS:
55056-80-9
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C51H84O22/c1-20(19-65-45-39(60)38(59)35(56)30(17-52)69-45)9-14-51(64)21(2)32-29(73-51)16-28-26-8-7-24-15-25(10-12-49(24,5)27(26)11-13-50(28,32)6)68-48-44(72-47-41(62)37(58)34(55)23(4)67-47)42(63)43(31(18-53)70-48)71-46-40(61)36(57)33(54)22(3)66-46/h7,20-23,25-48,52-64H,8-19H2,1-6H3/t20-,21+,22+,23+,25+,26-,27+,28+,29+,30-,31-,32+,33+,34+,35-,36-,37-,38+,39-,40-,41-,42+,43-,44-,45-,46+,47+,48-,49+,50+,51-/m1/s1
InChiKey:
LVTJOONKWUXEFR-UEZXSUPNSA-N
Long Description:
Chemical. CAS: 55056-80-9. Formula: C51H84O22. MW: 1049.2. Protodioscin is a steroidal saponin first isolated from plants, with anticancer, antihyperlipidemic, antioxidant, anti-inflammatory and neuroprotective properties. It displays cytotoxic, apoptosis incuding and antiproliferative activity against a range of cancer cells. Protodioscin has also been shown to have aphrodisiac properties.
MDL:
MFCD03427682
Molecular Formula:
C51H84O22
Molecular Weight:
1049.2
Package Type:
Vial
Product Description:
Protodioscin is a steroidal saponin first isolated from plants, with anticancer, antihyperlipidemic, antioxidant, anti-inflammatory and neuroprotective properties. It displays cytotoxic, apoptosis incuding and antiproliferative activity against a range of cancer cells. Protodioscin has also been shown to have aphrodisiac properties.
Purity:
>98% (HPLC)
SMILES:
C[C@]12C(C[C@@H](O[C@@](O[C@H](CO)[C@@H](O[C@]3([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H]4O)([H])[C@@H]4O[C@]5([H])O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)CC2)=CC[C@]6([H])[C@]1([H])CC[C@@]7(C)[C@@]6([H])C[C@@]8([H])[C@]7([H])[C@H](C)[C@@](O)(CC[C@@H](C)CO[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O)O8
Solubility Chemicals:
Soluble in DMSO (20mg/ml), DMF (5mg/ml) or ethanol (10mg/ml).
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) K. Hu & X. Yao; Planta Med. 68, 297 (2002) | (2) K. Gauthaman, et al.; Life Sci. 71, 1385 (2002) | (3) H. Hibasami, et al.; Int. J. Mol. Med. 11, 23 (2003) | (4) T. Wang, et al.; Planta Med. 76, 1642 (2010) | (5) X. Zhang, et al.; Steroids 113, 52 (2016) | (6) M. Oyama, et al.; Curr. Bioact. Compd. 13, 170 (2017) | (7) J.Y. Liu, et al.; Apoptosis 22, 1454 (2017) | (8) J. Wu, et al.; Pharmacol. Rep. 70, 139 (2018) | (9) C.L. Lin, et al.; Cell Physiol. Biochem. 46, 322 (2018) | (10) K. Shu & Y. Zhang; Cell Stress Chaperones 24, 1091 (2019)