Chemodex

Polydatin

Product Code:
 
CDX-P0596
Supplier:
 
Chemodex
Host Type:
 
Plant
Regulatory Status:
 
RUO
Shipping:
 
AMBIENT
Storage:
 
Short Term: +20°C Long Term: +4°C
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Chemical Structure

Chemical Structure

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CDX-P0596-G0011 g£48.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Piceid; Reservatrol-3-beta-mono-D-glucoside; Resveratrol 3-O-beta-D-glucopyranoside; 3,4'-5-Trihydroxystilbene-3-beta-D-glucopyranoside
Appearance:
White to yellow powder.
CAS:
65914-17-2
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16-,17-,18+,19-,20-/m1/s1
InChiKey:
HSTZMXCBWJGKHG-CUYWLFDKSA-N
Long Description:
Chemical. CAS: 65914-17-2. Formula: C20H22O8. MW: 390.38. Polydatin is a natural stilbene with antioxidant, anti-inflammatory, anticancer, neuroprotective, cardioprotective, anti-osteoporotic and antilipidemic properties. It has been shown to inhibit NF-kappa signaling pathway and the NLRP3 inflammasome activation. It is an apoptosis and autophagy inducer, cell cycle inhibitor, activator of SIRT1 and also inhibits adipogenesis.
MDL:
MFCD00210592
Molecular Formula:
C20H22O8
Molecular Weight:
390.38
Package Type:
Vial
Product Description:
Polydatin is a natural stilbene with antioxidant, anti-inflammatory, anticancer, neuroprotective, cardioprotective, anti-osteoporotic and antilipidemic properties. It has been shown to inhibit NF-kappa signaling pathway and the NLRP3 inflammasome activation. It is an apoptosis and autophagy inducer, cell cycle inhibitor, activator of SIRT1 and also inhibits adipogenesis.
Purity:
>98% (HPLC)
SMILES:
OC1=CC(/C=C/C2=CC=C(O)C=C2)=CC(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=C1
Solubility Chemicals:
Soluble in DMSO (30mg/ml), DMF (50mg/ml) or ethanol (30mg/ml).
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

References

(1) J. Du, et al.; Phytomedicine 16, 652 (2009) | (2) Q. Miao, et al.; Phytomedicine 19, 8 (2011) | (3) H. Ji, et al.; Brain Res. Bull. 87, 50 (2012) | (4) Q.H. Du, et al.; Pharm. Biol. 51, 1347 (2013) (Review) | (5) Y. Zhang, et al.; Oncol. Lett. 7, 295 (2014) | (6) J. Sun, et al.; Mol. Med. Rep. 10, 3047 (2014) | (7) J. Hao, et al.; Eur. J. Pharmacol. 745, 152 (2014) | (8) H.L. Wang, et al.; Phytomedicine 22, 553 (2015) | (9) Y. Chen, et al.; Mol. Neurodegener. 10, 4 (2015) | (10) Z. Zeng, et al.; J. Surg. Res. 198, 192 (2015) | (11) Z. Zeng, et al.; Oxid. Med. Cell Longev. 2015, 965961 (2015) | (12) Y. Ma, et al.; Int. J. Mol. Med. 37, 1652 (2016) | (13) Q.L. Zhou, et al.; Mol. Med. Rep. 14, 1865 (2016) | (14) J. Jin, et al.; Adv. Exp. Med. Biol. 923, 57 (2016) | (15) B. Yang & S. Zhao; Onco. Targets Ther. 10, 935 (2017) | (16) J. Zou, et al.; Biomed. Pharmacother. 108, 130 (2018) | (17) Y.L. Jin, et al.; Onco. Targets Ther. 11, 8185 (2018) | (18) J. Tang, et al.; J. Cell Biochem. 120, 10137 (2019)