Galangin
Product Code:
CDX-G0216
CDX-G0216
Host Type:
Plant
Plant
Regulatory Status:
RUO
RUO
Shipping:
AMBIENT
AMBIENT
Storage:
Short Term: +4°C, Long Term: -20°C
Short Term: +4°C, Long Term: -20°C
No additional charges, what you see is what you pay! *
| Code | Size | Price |
|---|
| CDX-G0216-M025 | 25 mg | £96.00 |
Quantity:
| CDX-G0216-M100 | 100 mg | £273.00 |
Quantity:
Prices exclude any Taxes / VAT
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* Rare exceptions are clearly labelled (only 0.14% of items!).
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This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
- Further Information
- Documents
- References
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Further Information
Alternate Names/Synonyms:
3,5,7-Trihydroxyflavone; Norizalpinin; NSC 407229
Appearance:
Light yellow powder.
CAS:
548-83-4
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315-H319-H335
InChi:
InChI=1S/C15H10O5/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8/h1-7,16-17,19H
InChiKey:
VCCRNZQBSJXYJD-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 548-83-4. Formula: C15H10O5. MW: 270.24. Galangin is a flavonoid naturally found in herbs used in traditional medicine. It has diverse biological activities, including potent antioxidant, anti-inflammatory, antiobesity, antidiabetic, anti-cancer, neuroprotective, antiviral and antibacterial properties. Galangin has anti-inflammatory actions related to suppression of signaling through NF-kappa/NRLP3 pathway. Galangin induces apoptosis and autophagy in different cancer cells. It is a TRPC5 inhibitor, inhibiting Ca2+ entry into TRPC5 expressing cells. Galangin as a potential DPP-4 inhibitor that improves insulin-stimulated skeletal muscle glucose uptake.
MDL:
MFCD00006833
Molecular Formula:
C15H10O5
Molecular Weight:
270.24
Package Type:
Vial
Precautions:
P261-P305 + P351 + P338
Product Description:
Galangin is a flavonoid naturally found in herbs used in traditional medicine. It has diverse biological activities, including potent antioxidant, anti-inflammatory, antiobesity, antidiabetic, anti-cancer, neuroprotective, antiviral and antibacterial properties. Galangin has anti-inflammatory actions related to suppression of signaling through NF-kappa/NRLP3 pathway. Galangin induces apoptosis and autophagy in different cancer cells. It is a TRPC5 inhibitor, inhibiting Ca2+ entry into TRPC5 expressing cells. Galangin as a potential DPP-4 inhibitor that improves insulin-stimulated skeletal muscle glucose uptake.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
OC1=C2C(OC(C3=CC=CC=C3)=C(O)C2=O)=CC(O)=C1
Solubility Chemicals:
Soluble in DMSO (20mg/ml), DMF (20mg/ml) or ethanol (10mg/ml).
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
Documents
References
(1) J.J. Meyer, et al.; J. Ethnopharmacol. 56, 165 (1997) | (2) S. Pepeljnjak & I. Kosalec; FEMS Microbiol. Lett. 240, 111 (2004) | (3) H.T. Zhang, et al.; World J. Gastroenterol. 16, 3377 (2010) | (4) M. Wen, et al.; Pharmacology 89, 247 (2012) | (5) W. Zhang, et al.; J. Cell Biochem. 114, 152 (2013) | (6) S. Kumar & K.R. Alagawadi; Pharm. Biol. 51, 607 (2013) | (7) S. Shaikh, et al.; CNS Neurol. Disord. Drug Targets 13, 452 (2014) | (8) Y.C. Jung, et al.; Immunopharmacol. Immunotoxicol. 36, 426 (2014) | (9) J. Naylor, et al.; Br. J. Pharmacol. 173, 562 (2016) | (10) G. Chen, et al.; Int. J. Mol. Sci. 19, E12 (2017) | (11) A.A. Aloud, et al.; Redox Rep. 23, 29 (2018) | (12) Q. Fu, et al.; Mol. Med. Rep. 18, 3619 (2018) | (13) M.E. Kim, et al.; Mol. Cell Biochem. 451, 145 (2019) | (14) P. Kalhotra, et al.; Int. J. Mol. Sci. 20, E1228 (2019)