7-Hydroxy-4-coumarinylacetic acid
| Code | Size | Price |
|---|
| CDX-H0008-G005 | 5 g | £96.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +4°C Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
7-HCA; 7-Hydroxycoumarin-4-acetic acid; Umbelliferone-4-acetic acid; NSC 642907; NSC 65625
Appearance:
Beige powder.
CAS:
6950-82-9
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315-H319-H335
InChi:
InChI=1S/C11H8O5/c12-7-1-2-8-6(3-10(13)14)4-11(15)16-9(8)5-7/h1-2,4-5,12H,3H2,(H,13,14)
InChiKey:
BNHPMQBVNXMPDU-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 6950-82-9. Formula: C11H8O5. MW: 220.18. 7-Hydroxycoumarin-4-acetic acid is a fluorescent pH indicator. 7-Hydroxycoumarin-4-acetic acid is used for labeling amine-specific peptides, proteins and other biological molecules to give blue fluorescence. It is used as fluorigenic substrate, e.g. in BSA-HCA complexes for fatty acid concentration measurement or for fluorometric enzymatic analysis. It also can be used as a building block for synthesis of other coumarin-based probes. Spectral data: lambdaEx=360nm; lambdaEm=450nm (DMSO).
MDL:
MFCD00037563
Molecular Formula:
C11H8O5
Molecular Weight:
220.18
Package Type:
Vial
Precautions:
P261-P305 + P351 + P338
Product Description:
7-Hydroxycoumarin-4-acetic acid is a fluorescent pH indicator. 7-Hydroxycoumarin-4-acetic acid is used for labeling amine-specific peptides, proteins and other biological molecules to give blue fluorescence. It is used as fluorigenic substrate, e.g. in BSA-HCA complexes for fatty acid concentration measurement or for fluorometric enzymatic analysis. It also can be used as a building block for synthesis of other coumarin-based probes. Spectral data: lambdaEx=360nm; lambdaEm=450nm (DMSO).
Purity:
>98% (NMR)
Signal Word:
Warning
SMILES:
OC1=CC=C2C(OC(C=C2CC(O)=O)=O)=C1
Solubility Chemicals:
Soluble in DMSO or methanol.
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) G. Gabor & D.R. Walt; Anal. Chem. 63, 793 (1991) | (2) E.J.F. Demant; BBA 1304, 43 (1996) | (3) J.F. Sierra, et al.; Anal. Chim. Acta 368, 97 (1998) | (4) E.J.F. Demant; Anal. Biochem. 267, 366 (1999) | (5) C. Charitos, et al.; J. Heterocyclic Chem. 38, 153 (2001) | (6) K.F. Chilvers, et al.; J. Appl. Microbiol. 91, 1118 (2001) | (7) S. Chen, et al.; Anal. Meth. 7, 7646 (2015) | (8) L. Rong, et al.; Chem. Commun. 50, 667 (2014)