Chemodex

Mangiferin

Product Code:
 
CDX-M0465
Supplier:
 
Chemodex
Host Type:
 
Plant
Regulatory Status:
 
RUO
Shipping:
 
AMBIENT
Storage:
 
Short Term: +4°C Long Term: -20°C
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Chemical Structure

Chemical Structure

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CDX-M0465-G0011 g£242.00
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
MGF; 1,3,6,7-Tetrahydroxyxanthone C2-beta-D-glucoside; NSC 248870
Appearance:
Light yellow powder.
CAS:
4773-96-0
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C19H18O11/c20-4-11-15(25)17(27)18(28)19(30-11)12-8(23)3-10-13(16(12)26)14(24)5-1-6(21)7(22)2-9(5)29-10/h1-3,11,15,17-23,25-28H,4H2/t11-,15-,17+,18-,19+/m1/s1
InChiKey:
AEDDIBAIWPIIBD-ZJKJAXBQSA-N
Long Description:
Chemical. CAS: 4773-96-0. Formula: C19H18O11. MW: 422.34. Mangiferin is a xanthone glucoside that has been found in M. indica with diverse biological activities, including analgesic, antidiabetic, antisclerotic, antimicrobial and antiviral, cardio-, hepato-, and neuroprotective, anti-inflammatory, immunomodulatory, anticancer, as well as radioprotective against X-ray, gamma and UV radiation effects. It is also used in cosmetics, due to antioxidant and UV-protecting properties. The anti-inflammatroy activity is through inhibiting NF-kappa and NLRP3 signaling pathways.
MDL:
MFCD00075656
Molecular Formula:
C19H18O11
Molecular Weight:
422.34
Package Type:
Vial
Precautions:
P301 + P312 + P330
Product Description:
Mangiferin is a xanthone glucoside that has been found in M. indica with diverse biological activities, including analgesic, antidiabetic, antisclerotic, antimicrobial and antiviral, cardio-, hepato-, and neuroprotective, anti-inflammatory, immunomodulatory, anticancer, as well as radioprotective against X-ray, gamma and UV radiation effects. It is also used in cosmetics, due to antioxidant and UV-protecting properties. The anti-inflammatroy activity is through inhibiting NF-kappa and NLRP3 signaling pathways.
Purity:
>98% (HPLC)
Signal Word:
Warning
SMILES:
OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](C2=C(O)C(C(C(C=C(O)C(O)=C3)=C3O4)=O)=C4C=C2O)O1
Solubility Chemicals:
Soluble in DMSO (5mg/ml) or DMF (2mg/ml).
Source / Host:
Plant
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

(1) F. Gold-Smith, et al.; Nutrients 8, E396 (2016) (Review) | (2) S. Saha, et al.; Biofactors 42, 459 (2016) (Review) | (3) A.J. Nunez Selles, et al.; Biofactors 42, 475 (2016) (Review) | (4) E.V. Fomenko & Y. Chi; Biofactors 42, 492 (2016) (Review) | (5) M. Imran, et al.; Lipids Health Dis. 16, 84 (2017) (Review) | (6) S. Du, et al.; Mol. Med. Rep. 18, 4775 (2018) (Review) | (7) F. Quadri, et al.; Expert Opin. Ther. Pat. 29, 463 (2019) (Review) | (8) S.T. Feng, et al.; Pharmacol. Res. 146, 104336 (2019) (Review)