Ginkgolide C
| Code | Size | Price |
|---|
| CDX-G0214-M010 | 10 mg | £88.00 |
Quantity:
| CDX-G0214-M050 | 50 mg | £304.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Plant
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +4°C, Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
1,7-Dihydroxy-ginkgolide A; BN 52022
Appearance:
White to off-white powder.
CAS:
15291-76-6
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C20H24O11/c1-5-12(24)28-11-8(22)18-10-6(21)7(16(2,3)4)17(18)9(23)13(25)30-15(17)31-20(18,14(26)29-10)19(5,11)27/h5-11,15,21-23,27H,1-4H3/t5-,6-,7+,8+,9+,10-,11+,15+,17?,18?,19-,20-/m1/s1
InChiKey:
AMOGMTLMADGEOQ-AEXCBEIUSA-N
Long Description:
Chemical. CAS: 15291-76-6. Formula: C20H24O11. MW: 440.4. Isolated from plant source. Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist. Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes via the activated AMPK pathway. Shown to inhibit CD40-NF-kappaB pathway. Can be used as a reference compound.
MDL:
MFCD02094178
Molecular Formula:
C20H24O11
Molecular Weight:
440.4
Package Type:
Vial
Product Description:
Ginkgolide C is a flavone first extracted from G. biloba leaves with multiple reported biological functions. It has been identified as a selective platelet activating factor receptor antagonist. Ginkgolide C has also been shown to increase lipolysis and to inhibit adipogenesis in adipocytes via the activated AMPK pathway. Shown to inhibit CD40-NF-kappaB pathway. Can be used as a reference compound.
Purity:
>98% (HPLC)
SMILES:
O=C(O1)[C@@H](C)[C@]([C@]1([H])[C@@H]2O)(O)[C@@]3(C4=O)C2([C@H](O4)[C@H](O)[C@H]5C(C)(C)C)C5([C@@H](O)C(O6)=O)[C@]6([H])O3
Solubility Chemicals:
Soluble in DMSO, DMF. Acetone, Ethanol, Ethyl Acetate, Dioxane and Methanol
Source / Host:
Isolated from plant source.
Transportation:
Non-hazardous
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) P. Braquet, et al.; Med. Res. Rev. 11, 295 (1991) (Review) | (2) C.-J. Liou, et al.; Evid.-Based Compl. Altern. Med. 2015, 298635 (2015) | (3) R. Zhang, et al.; Front. Pharmacol. 9, 109 (2018)