Spinosyn A
| Code | Size | Price |
|---|
| CDX-S0293-M100 | 100 mg | £188.00 |
Quantity:
| CDX-S0293-G001 | 1 g | £1,366.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
A-83543A; Lepicidin A
Appearance:
White powder.
CAS:
131929-60-7
Class:
9
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS09
Handling Advice:
Protect from light and moisture.
Hazards:
H410
InChi:
InChI=1S/C41H65NO10/c1-10-26-12-11-13-34(52-36-17-16-33(42(5)6)23(3)48-36)22(2)37(44)32-20-30-28(31(32)21-35(43)50-26)15-14-25-18-27(19-29(25)30)51-41-40(47-9)39(46-8)38(45-7)24(4)49-41/h14-15,20,22-31,33-34,36,38-41H,10-13,16-19,21H2,1-9H3/t22-,23-,24+,25-,26+,27-,28+,29-,30-,31+,33+,34+,36+,38+,39-,40-,41+/m1/s1
InChiKey:
SRJQTHAZUNRMPR-IRXCAFTDSA-N
Long Description:
Chemical. CAS: 131929-60-7. Formula: C41H65NO10. MW: 731.95. Spinosyn A is a naturally-occurring macrocyclic lactone that is a potent insecticide. It is the main component of Spinosad working as a larvicide but also has activity on adult insects and eggs. It is active on Lepdioptera, Thysanoptera, Hymenoptera, Diptera and Coleoptera. It acts as an agonist of insect nicotinic acetylcholinesterase receptors (nAChRs), which differ both structurally and functionally from nAChRs in vertebrates. As a result, it has low affinity for vertebrate nAChRs and has limited adverse effects in those animals. This agent can be used as a reference compound.
MDL:
MFCD01753923
Molecular Formula:
C41H65NO10
Molecular Weight:
731.95
Package Type:
Vial
PG:
III
Precautions:
P273-P391-P501
Product Description:
Spinosyn A is a naturally-occurring macrocyclic lactone that is a potent insecticide. It is the main component of Spinosad working as a larvicide but also has activity on adult insects and eggs. It is active on Lepdioptera, Thysanoptera, Hymenoptera, Diptera and Coleoptera. It acts as an agonist of insect nicotinic acetylcholinesterase receptors (nAChRs), which differ both structurally and functionally from nAChRs in vertebrates. As a result, it has low affinity for vertebrate nAChRs and has limited adverse effects in those animals. This agent can be used as a reference compound.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
O=C(C[C@]1([H])C2=C[C@]3([H])[C@]1([H])C=C[C@@]4([H])[C@@]3([H])C[C@H](O[C@]5([H])O[C@@H](C)[C@H](OC)[C@@H](OC)[C@H]5OC)C4)O[C@@H](CC)CCC[C@H](O[C@]6([H])O[C@H](C)[C@@H](N(C)C)CC6)[C@@H](C)C2=O
Solubility Chemicals:
Soluble in DMSO, DMF, ethanol or methanol. Insoluble in water.
Source / Host:
Microbial
Transportation:
Excepted Quantity
UN Nummer:
3077
UNSPSC Category:
Natural Products/Extracts
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) L.C. Creemer, et al.; J. Antibiot. 53, 171 (2000) | (2) D.J. Mergott, et al.; PNAS 101, 11955 (2004) | (3) S.O. Duke, et al.; Toxins 2, 1943 (2010) | (4) D.T. Vo, et al.; J. Vet. Pharmacol. Ther. 33, 315 (2010) | (5) T.S. Amaral, et al.; Braz. J. Biol. 72, 299 (2012)