6-Chloropurine
| Code | Size | Price |
|---|
| CDX-C0684-G005 | 5 g | £65.00 |
Quantity:
| CDX-C0684-G025 | 25 g | £230.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
6-Chloro-9H-purine
Appearance:
Light yellow powder.
CAS:
87-42-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302
InChi:
InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)
InChiKey:
ZKBQDFAWXLTYKS-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 87-42-3. Formula: C5H3ClN4. MW: 154.56. 6-Chloropurine is a building block in chemical synthesis and is used as an intermediate in the preparation of 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO. 6-Chloropurine based compounds have been shown to display antiviral and antitumor properties.
MDL:
MFCD00075825
Molecular Formula:
C5H3ClN4
Molecular Weight:
154.56
Package Type:
Vial
Product Description:
6-Chloropurine is a building block in chemical synthesis and is used as an intermediate in the preparation of 9-alkylpurines via alkylation with various substituted alkyl halides in DMSO. 6-Chloropurine based compounds have been shown to display antiviral and antitumor properties.
Purity:
>98% (HPLC)
Signal word:
Warning
SMILES:
ClC1=C2C(NC=N2)=NC=N1
Solubility Chemicals:
Soluble in DMSO (20mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) A.C. Sartorelli, et al.; J. Pharmacol. Exp. Ther. 134, 123 (1961) | (2) J.A. Montgomery & C. Temple; JACS 83, 630 (1961) | (3) M. Fuertes, et al.; Tetrahedron 26, 4823 (1970) | (4) I.Y. Hwang, et al.; J. Pharmacol. Exp. Ther. 264, 41 (1993) | (5) E. Kierzek & R. Kierzek; Curr. Protoc. Nucleic Acid Chem. Chapter 4, Unit 4.23 (2004) | (6) P. Plackova, et al.; J. Enzyme Inhib. Med. Chem. 30, 57 (2015) | (7) S. Schwarz, et al.; Eur. J. Med. Chem. 90, 595 (2015)