5,5'-Difluoro BAPTA-AM
| Code | Size | Price |
|---|
| CDX-B0445-M010 | 10 mg | £121.00 |
Quantity:
| CDX-B0445-M050 | 50 mg | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
5FBAPTA-AM; 1,2-Bis(2-amino-5-fluorophenoxy)ethane-N,N,N',N'-tetraacetic acid tetrakis(acetoxymethyl) ester
Appearance:
White to off-white crystalline powder.
CAS:
128255-42-5
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H315-H319-H335
InChi:
InChI=1S/C34H38F2N2O18/c1-21(39)49-17-53-31(43)13-37(14-32(44)54-18-50-22(2)40)27-7-5-25(35)11-29(27)47-9-10-48-30-12-26(36)6-8-28(30)38(15-33(45)55-19-51-23(3)41)16-34(46)56-20-52-24(4)42/h5-8,11-12H,9-10,13-20H2,1-4H3
InChiKey:
ZXXWTKAFGAXGHZ-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 128255-42-5. Formula: C34H38F2N2O18. MW: 800.66. 5,5?-Difluoro-BAPTA-AM is a calcium chelator that may be used to modulate calcium levels and flow within cells to study calcium homeostasis and cell signaling. It is used to study cytosolic free Ca2+ by 19F-NMR. It has high selectivity for Ca2+, it is not particularly pH sensitive and is available protected as its acetoxymethyl ester. Determination with 5,5?-Difluoro-BAPTA-AM are not sensitive to cells which have a high natural background fluorescence.
MDL:
MFCD00467468
Molecular Formula:
C34H38F2N2O18
Molecular Weight:
800.66
Package Type:
Vial
Precautions:
P261-P305+P351+P338
Product Description:
5,5?-Difluoro-BAPTA-AM is a calcium chelator that may be used to modulate calcium levels and flow within cells to study calcium homeostasis and cell signaling. It is used to study cytosolic free Ca2+ by 19F-NMR. It has high selectivity for Ca2+, it is not particularly pH sensitive and is available protected as its acetoxymethyl ester. Determination with 5,5?-Difluoro-BAPTA-AM are not sensitive to cells which have a high natural background fluorescence.
Purity:
>97% (HPLC)
Signal word:
Warning
SMILES:
O=C(OCOC(C)=O)CN(CC(OCOC(C)=O)=O)C1=CC=C(F)C=C1OCCOC2=CC(F)=CC=C2N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O
Solubility Chemicals:
Soluble in DMSO, DMF, EtOAc or CHCl3.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) G.A. Smith, et al.; PNAS 80, 7178 (1983) | (2) E. Marban, et al.; Circul. Res. 66, 1255 (1990) | (3) P.E. Morris; Org. Prep. Proc. Int. 25, 445 (1993) | (4) A.R. Waldeck, et al.; Eur. Biophys. J. 27, 247 (1998)