N-Dansylethylenediamine
| Code | Size | Price |
|---|
| CDX-C0068-M500 | 500 mg | £280.00 |
Quantity:
| CDX-C0068-G001 | 1 g | £450.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
-20°C
Documents
Further Information
Alternate Names/Synonyms:
N-Dansylethylenediamine; N-(2-Aminoethyl)-5-dimethylamino-1-naphthalenesulfonamide; N-(2-Aminoethyl)dansylamide; DNSEDA; NSC 666752; Dansyl EDA
Appearance:
Yellow to orange powder.
CAS:
35060-08-3
EClass:
32160000
Form (Short):
liquid
GHS Symbol:
GHS07
Handling Advice:
Protect from light and moisture.
Hazards:
H302-H315-H319-H335
InChi:
InChI=1S/C14H19N3O2S/c1-17(2)13-7-3-6-12-11(13)5-4-8-14(12)20(18,19)16-10-9-15/h3-8,16H,9-10,15H2,1-2H3
InChiKey:
CSJXLKVNKAXFSI-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 35060-08-3. Formula: C14H19N3O2S. MW: 293.38. Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: lambdaEx=335nm; lambdaEm=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
MDL:
MFCD00467523
Molecular Formula:
C14H19N3O2S
Molecular Weight:
293.38
Package Type:
Vial
Precautions:
P261-P305+P351+P338
Product Description:
Dansyl ethylenediamine is a lipophilic fluorophore that can be coupled to coarboxylic acids of proteins and other water-soluble polymers. The primary aliphatic amine of dansyl ethylenediamine can be reversibly coupled to aldehydes and ketones to form a Schiff base, which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Spectral data: lambdaEx=335nm; lambdaEm=525nm in methanol. Dansyl ethylenediamine has also shown to inhibit human renal dipeptidase (hrDP) irreversibly in a time-dependent manner.
Purity:
>97% (NMR)
Signal word:
Warning
SMILES:
CN(C)C1=C(C=CC=C2S(=O)(NCCN)=O)C2=CC=C1
Solubility Chemicals:
Slightly soluble in methanol (1 mg/ml).
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) H. Adachi, et al.; Biochim. Biophys. Acta 1163, 42 (1993) | (2) A. Sonoki, et al.; J. Liqu. Chrom. Rel. Technol. 17, 1057 (1994) | (3) J. Moraczewska, et al.; Biophys J. 77, 373 (1999) | (4) L. Prodi, et al.; Hel. Chim. Acta 84, 690 (2001) | (5) S. Mallampati, et al.; Electrophoresis 28, 3948 (2007) | (6) R.W. Dudley, et al.; Mol. Cell Biochem. 346, 81 (2011) | (7) Y. Inoue, et al.; Biosens. Bioelectron. 48, 113 (2013)