Procaine hydrochloride
| Code | Size | Price |
|---|
| CDX-P0182-M250 | 250 mg | £48.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +20°C Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
4-Aminobenzoic acid 2-diethylaminoethyl ester; p-Aminobenzoic acid diethylaminoethyl ester hydrochloride; Novocaine hydrochloride
Appearance:
White to off-white powder.
CAS:
51-05-8
Class:
6.1
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS06
Handling Advice:
Protect from light and moisture.
Hazards:
H301-H317
InChi:
InChI=1S/C13H20N2O2.ClH/c1-3-15(4-2)9-10-17-13(16)11-5-7-12(14)8-6-11;/h5-8H,3-4,9-10,14H2,1-2H3;1H
InChiKey:
HCBIBCJNVBAKAB-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 51-05-8. Formula: C13H20N2O2 . HCl. MW: 272.77. Synthetic. Procaine is a sodium channel blocker, commonly used as an anesthetic agent and a variety of other inhibitiory effects. It is also useful as a painkiller to prevent or relieve pain for short periods, such as during dental procedures. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR) and to inhibit nicotinic acetylcholine receptors. It has been shown to be a DNA methylation inhibitor with anti-tumor activity. Inhibited also HERG channels. Can be used as an analytical reference compound, since procaine is used as an adulterant in illicit drugs.
MDL:
MFCD00013000
Molecular Formula:
C13H20N2O2 . HCl
Molecular Weight:
272.77
Package Type:
Vial
PG:
III
Precautions:
P280-P301 + P310
Product Description:
Procaine is a sodium channel blocker, commonly used as an anesthetic agent and a variety of other inhibitiory effects. It is also useful as a painkiller to prevent or relieve pain for short periods, such as during dental procedures. In skeletal muscle, Procaine has been reported to inhibit calcium-induced calcium release (CICR) and to inhibit nicotinic acetylcholine receptors. It has been shown to be a DNA methylation inhibitor with anti-tumor activity. Inhibited also HERG channels. Can be used as an analytical reference compound, since procaine is used as an adulterant in illicit drugs.
Purity:
>98% (HPLC)
Signal Word:
Danger
SMILES:
NC1=CC=C(C(OCC[NH+](CC)CC)=O)C=C1.[Cl-]
Solubility Chemicals:
Soluble in water or ethanol.
Source / Host:
Synthetic
Transportation:
Excepted Quantity
UN Nummer:
2811
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) S. Epstein & N.W. Chilton; Oral Surg. Oral Med. Oral Pathol. 12, 93 (1959) | (2) R. Werdehausen, et al.; Br. J. Anaesth. 103, 711 (2009) | (3) Z. Gao, et al.; Oncol. Rep. 22, 1479 (2009) | (4) M. Endo; Physiol. Rev. 89, 1153 (2009) | (5) H. Wang, et al.; Eur. J. Pharmacol. 630, 29 (2010) | (6) R. Gal & F. Libersat; PLoS ONE 5, e10019 (2010) | (7) C. Cole, et al.; CUT (2010) | (8) N. Wang, et al.; J. Pharmacol. Sci. 123, 25 (2013) | (9) C. Li, et al.; Oncol. Res. 26, 209 (2018) | (10) Y.C. Li, et al.; J. Cell Biochem. 119, 2440 (2018)