Litihium Ionophore III
| Code | Size | Price |
|---|
| CDX-L0123-M050 | 50 mg | £291.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +4°C Long Term: -20°C
Documents
Further Information
Alternate Names/Synonyms:
ETH 1810; N,N-Dicyclohexyl-N',N'-diisobutyl-cis-cyclohexane-1,2-dicarboxamide
Appearance:
White powder.
CAS:
99281-50-2
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C28H50N2O2/c1-21(2)19-29(20-22(3)4)27(31)25-17-11-12-18-26(25)28(32)30(23-13-7-5-8-14-23)24-15-9-6-10-16-24/h21-26H,5-20H2,1-4H3/t25-,26+/m0/s1
InChiKey:
QGKITQHJONXIQV-IZZNHLLZSA-N
Long Description:
Chemical. CAS: 99281-50-2. Formula: C28H50N2O2. MW: 446.71. Lithium ionophore III (ETH 1810) has been used in liquid membrane electrodes for the determination of Li concentration in blood. It is a neutral non-cyclic Li(+)-selective ionophore, which can transport lithium and other monovalent cations, across lipid bilayer membranes, forming 2:1 ionophore:ion membrane-permeating species. The selectivity is Li+ > Na+ > K+ > Cs+. ETH 1810 was also found to be capable of acting as a carrier of biogenic amines and related molecules, with the following selectivity sequence: Tryptamine > Phenylethylamine > Tyramine > Serotonin > Li+ > NH+4 > Dopamine. Protons at physiological concentrations do not interfere with the lithium transport.
MDL:
MFCD00077936
Molecular Formula:
C28H50N2O2
Molecular Weight:
446.71
Package Type:
Vial
Product Description:
Lithium ionophore III (ETH 1810) has been used in liquid membrane electrodes for the determination of Li concentration in blood. It is a neutral non-cyclic Li(+)-selective ionophore, which can transport lithium and other monovalent cations, across lipid bilayer membranes, forming 2:1 ionophore:ion membrane-permeating species. The selectivity is Li+ > Na+ > K+ > Cs+. ETH 1810 was also found to be capable of acting as a carrier of biogenic amines and related molecules, with the following selectivity sequence: Tryptamine > Phenylethylamine > Tyramine > Serotonin > Li+ > NH+4 > Dopamine. Protons at physiological concentrations do not interfere with the lithium transport.
Purity:
>98% (HPLC)
SMILES:
O=C(N(C1CCCCC1)C2CCCCC2)[C@H]3[C@@H](C(N(CC(C)C)CC(C)C)=O)CCCC3
Solubility Chemicals:
Soluble in chlorofrom or DCM.
Source / Host:
Synthetic
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.
References
(1) E. Metzger et al. Anal. Chem. 59, 1600, (1987) | (2) A. Zeevi & R. Margalit; J. Membr. Biol. 121, 133 (1991) | (3) A. Zeevi & R. Margalit; Arch. Biochem. Biophys. 298, 84 (1992) | (4) E. Bakker & E. Pretsch; Anal. Chem. 70, 295 (1998)