Midodrine hydrochloride
| Code | Size | Price |
|---|
| CDX-M0238-G001 | 1 g | £242.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
+20°C
Documents
Further Information
Alternate Names/Synonyms:
(?)-1-(2,5-Dimethoxyphenyl)-2-glycinamidoethanol
Appearance:
White to off-white powder.
CAS:
3092-17-9
Class:
6.1
EClass:
32160000
Form (Short):
solid
GHS Symbol:
GHS06
Handling Advice:
Protect from light and moisture.
Hazards:
H301
InChi:
InChI=1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H
InChiKey:
MGCQZNBCJBRZDT-UHFFFAOYSA-N
Long Description:
Chemical. CAS: 3092-17-9. Formula: C12H18N2O4 . HCl. MW: 290.74. Midodrine is a vasopressor/antihypotensive agent and a long acting alpha-adrenergic stimulating agent. Midodrine is a prodrug which forms an active metabolite, desglymidodrine, which is an alpha1-receptor agonist and exerts its actions via activation of the alpha-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
MDL:
MFCD00079455
Molecular Formula:
C12H18N2O4 . HCl
Molecular Weight:
290.74
Package Type:
Vial
PG:
III
Precautions:
P301 + P310
Product Description:
Midodrine is a vasopressor/antihypotensive agent and a long acting alpha-adrenergic stimulating agent. Midodrine is a prodrug which forms an active metabolite, desglymidodrine, which is an alpha1-receptor agonist and exerts its actions via activation of the alpha-adrenergic receptors of the arteriolar and venous vasculature, producing an increase in vascular tone and elevation of blood pressure.
Purity:
>98% (HPLC)
Signal Word:
Danger
SMILES:
OC(CNC(CN)=O)C1=C(OC)C=CC(OC)=C1.Cl
Solubility Chemicals:
Soluble in DMSO (10mg/ml), DMF (2mg/ml) or water (0.5mg/ml).
Transportation:
Excepted Quantity
UN Nummer:
2811
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at RT.
References
(1) H. Pittner; Naunyn Schmiedebergs Arch. Pharmacol. 287, R22 (1975) | (2) D. McTavish & K.L. Goa; Drugs 38, 757 (1989) (Review) | (3) D.N. Cruz; Expert Opin. Pharmacother. 1, 835 (2000) (Review)