4-Methylumbelliferyl beta-D-glucuronide dihydrate
| Code | Size | Price |
|---|
| CDX-M0076-G001 | 1 g | £102.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
+4°C
Documents
Further Information
Alternate Names/Synonyms:
4-Methylumbelliferyl-?-D-glucopyranosiduronic acid; MUG; 4-MUG; 4-MU-glcUA; MUGlcU
Appearance:
Colourless to white crystalline powder.
CAS:
881005-91-0 | 6160-80-1 (anhydrous)
EClass:
32160000
Form (Short):
solid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1
InChiKey:
ARQXEQLMMNGFDU-JHZZJYKESA-N
Long Description:
Chemical. CAS: 881005-91-0 | 6160-80-1 (anhydrous). Formula: C16H16O9 . xH2O. MW: 352.29. 4-Methylumbelliferyl-beta-D-glucuronic acid dihydrate (MUG) is a non-fluorescent but fluorogenic beta-glucuronidase substrate. Once cleaved, MUG yields blue fluorescence seen under UV light. The substrate is commonly used for rapid sensitive identification of Escherichia coli contamination and for detecting marker GUS gene expression in plants with high sensitivity. In microbiology it is a component in Violet Red Bile Agar and Lauryl Tryptose Broth, for the detection of coliform organisms in water, food and dairy products. Spectral Data. lambdaEx/lambdaEm= 360/450 nm (cleaved product). MUG both directly and indirectly inhibits hyaluronan (HA) synthesis.
MDL:
MFCD09039280
Molecular Formula:
C16H16O9 . xH2O
Molecular Weight:
352.29
Package Type:
Vial
Product Description:
4-Methylumbelliferyl-beta-D-glucuronic acid dihydrate (MUG) is a non-fluorescent but fluorogenic beta-glucuronidase substrate. Once cleaved, MUG yields blue fluorescence seen under UV light. The substrate is commonly used for rapid sensitive identification of Escherichia coli contamination and for detecting marker GUS gene expression in plants with high sensitivity. In microbiology it is a component in Violet Red Bile Agar and Lauryl Tryptose Broth, for the detection of coliform organisms in water, food and dairy products. Spectral Data. lambdaEx/lambdaEm= 360/450 nm (cleaved product). MUG both directly and indirectly inhibits hyaluronan (HA) synthesis.
Purity:
>99% (HPLC)
SMILES:
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](C(O)=O)O[C@H]1OC2=CC(OC(C=C3C)=O)=C3C=C2
Solubility Chemicals:
Soluble in DMSO (50mg/ml) or water.
Transportation:
Non-hazardous
UNSPSC Category:
Fluorescent Reagents
UNSPSC Number:
41105331
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) P.C. Feng & P.A. Hartman; Appl. Environ. Microbiol. 43, 1320 (1982) | (2) B. Sperker, et al.; J. Chromatogr. B Biomed. Sci. Appl. 685, 181 (1996) | (3) P. Villari, et al.; Lett. Appl. Microbiol. 24, 286 (1997) | (4) S. Fior, et al.; Plant Sci. 176, 130 (2009) | (5) N. Nagy, et al.; JBC 294, 7864 (2019)