Adenosine
| Code | Size | Price |
|---|
| CDX-A0657-G050 | 50 g | £114.00 |
Quantity:
| CDX-A0657-G100 | 100 g | £181.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
AMBIENT
Storage:
Short Term: +20°C, Long Term: +4°C
Documents
Further Information
Alternate Names/Synonyms:
9-beta-D-Ribofuranosyladenine; Adenine riboside; Adenine-9-beta-D-ribofuranoside; NSC 7652
Appearance:
White to off white powder.
CAS:
58-61-7
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Protect from light and moisture.
InChi:
InChI=1S/C10H13N5O4/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(18)6(17)4(1-16)19-10/h2-4,6-7,10,16-18H,1H2,(H2,11,12,13)/t4-,6-,7-,10-/m1/s1
InChiKey:
OIRDTQYFTABQOQ-KQYNXXCUSA-N
Long Description:
Chemical. CAS: 58-61-7. Formula: C10H13N5O4. MW: 267.24. Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. Adenosine is a key endogenous neurotransmitter that regulates tissue function in an anti- and pro-inflammatory manner by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3, which serve diverse roles related to smooth muscle tone, central nervous system regulation and cardiac function. Cells of the immune system express these receptors and are responsive to the modulatory effects of adenosine in an inflammatory environment. Adenosine is a precursor for adenosine 5?-monophosphate, adenosine 5?-diphosphate, adenosine 5?-triphosphate and cyclic AMP.
MDL:
MFCD00005752
Molecular Formula:
C10H13N5O4
Molecular Weight:
267.24
Package Type:
Vial
Product Description:
Adenosine is a purine nucleoside composed of adenine and ribose linked by a glycosidic linkage. Adenosine is a key endogenous neurotransmitter that regulates tissue function in an anti- and pro-inflammatory manner by activating four G-protein-coupled adenosine receptors: A1, A2A, A2B and A3, which serve diverse roles related to smooth muscle tone, central nervous system regulation and cardiac function. Cells of the immune system express these receptors and are responsive to the modulatory effects of adenosine in an inflammatory environment. Adenosine is a precursor for adenosine 5?-monophosphate, adenosine 5?-diphosphate, adenosine 5?-triphosphate and cyclic AMP.
Purity:
>98% (HPLC)
SMILES:
O[C@H]1[C@@H](O)[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]1CO
Solubility Chemicals:
Soluble in water (7mg/ml) or DMSO (75 mM). Insoluble in ethanol.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.
References
(1) G. Hasko & B.N. Cronstein; Trends Immunol. 25, 33 (2004) | (2) K.A. Jacobson & Z.G. Gao; Nat. Rev. Drug Discov. 5, 247 (2006) (Review) | (3) G. Hasko, et al.; Nat. Rev. Drug Discov. 7, 759 (2008) (Review) | (4) S. Nakav, et al.; PLoS One 3, e2107 (2008)