FCGR1A Antibody / CD64

NSJ Bioreagents
Product Code: NSJ-V7768
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V7768-20UG20 ug£264.00
Quantity:
NSJ-V7768-100UG100 ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 10.1
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Store the CD64 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Images

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Flow cytometry staining of monocyte-gated human PBM cells with CD64 antibody (clone 10.1); Gray=isotype control, Red= CD64 antibody.~
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Flow cytometry staining of human U937 cells with CD64 antibody (clone 10.1); Gray=isotype control, Red=

Flow cytometry staining of monocyte-gated human PBM cells with CD64 antibody (clone 10.1); Gray=isotype control, Red= CD64 antibody.~
Flow cytometry staining of human U937 cells with CD64 antibody (clone 10.1); Gray=isotype control, Red=

Further Information

Application Details :
Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the antibody should be determined by the researcher.
Description:
Three different classes of IgG Fc receptors have been described: Fc stimulation. CD64 plays a putative role in the initiation of cell-mediated cytotoxicity. Thus far, three genes encoding four distinct CD64 transcripts have been described. CD64 has been shown to associate with signal transducing subunit of the high affinity IgE receptor. Src family kinases Hck and Lyn show increased kinase activity and will co-immunoprecipitate with CD64 subsequent to receptor cross linking.
Format :
Purified
Formulation :
0.2 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
Rheumatoid synovial fluid cells and human monocytes were used as the immunogen for the CD64 antibody.
Limitation:
This CD64 antibody is available for research use only.
Purity:
Protein G affinity chromatography
Species Reactivity :
Human
Uniprot #:
P12314