PCNA Antibody (Proliferating Cell Nuclear Antigen)
| Code | Size | Price |
|---|
| NSJ-F52380-0.08ML | 0.08 ml | £260.00 |
Quantity:
| NSJ-F52380-0.4ML | 0.4 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG1
Antibody Clonality: Monoclonal
Antibody Clone: 1157CT1.1.3
Regulatory Status: RUO
Target Species:
- Human
- Mouse
- Rat
Applications:
- Enzyme-Linked Immunosorbent Assay (ELISA)
- Immunohistochemistry (IHC)
- Western Blot (WB)
Storage:
Aliquot the PCNA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
IHC (Paraffin): 1:25,Western blot: 1:2000
Application Note:
Titration of the PCNA antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 236-261 from human Proliferating Cell Nuclear Antigen was used as the immunogen for this PCNA antibody.
Limitation:
This PCNA antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse, Rat
Species Reactivity (Predicted):
Bovine, Primate, Hamster
Uniprot #:
P12004