Thioredoxin Antibody / TRX / TXN
| Code | Size | Price |
|---|
| NSJ-F54201-0.05ML | 0.05 ml | £260.00 |
Quantity:
| NSJ-F54201-0.2ML | 0.2 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 1850CT339.14.1
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the Thioredoxin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Documents
Further Information
Application Details :
WB: 1:1000-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the Thioredoxin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Thioredoxin / TRX / TXN participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions. Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA-binding activity in ionizing radiation (IR) cells through its oxidation/reduction status and stimulates AP-1 transcriptional activity.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
Recominant human Thioredoxin protein was used as the immunogen for the Thioredoxin antibody.
Limitation:
This Thioredoxin antibody is available for research use only.
Purity:
Protein G purified
Species Reactivity :
Human
Uniprot #:
P10599