TSG101 Antibody
Code | Size | Price |
---|
NSJ-F54200-0.05ML | 0.05 ml | £260.00 |
Quantity:
NSJ-F54200-0.2ML | 0.2 ml | £502.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: IgG1, kappa
Antibody Clonality: Monoclonal
Antibody Clone: 1883CT788.47.15.46
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the TSG101 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Further Information
Application Details :
WB: 1:1000-1:2000
Application Note:
The stated application concentrations are suggested starting points. Titration of the TSG101 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding motif P-[ST]-A-P. This interaction is essential for viral particle budding of numerous retroviruses.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
Recombinant human TSG101 protein was used as the immunogen for the TSG101 antibody.
Limitation:
This TSG101 antibody is available for research use only.
Purity:
Protein G purified
Species Reactivity :
Human
Uniprot #:
Q99816